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Engineering of tissue inhibitor of metalloproteinases mutants as potential therapeutics
CHAPTER SUMMARY: Matrix metalloproteinases (MMPs) play a central role in many biological processes such as development, morphogenesis and wound healing, but their unbalanced activities are implicated in numerous disease processes such as arthritis, cancer metastasis, atherosclerosis, nephritis and f...
Autores principales: | Nagase, Hideaki, Brew, Keith |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2002
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3240149/ https://www.ncbi.nlm.nih.gov/pubmed/12110123 http://dx.doi.org/10.1186/ar573 |
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