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How are the regulators regulated? The search for mechanisms that impose specificity on induction of cell death and NF-κB activation by members of the TNF/NGF receptor family

CHAPTER SUMMARY: Signals emanating from receptors of the tumor necrosis factor/nerve growth factor (TNF/NGF) family control practically all aspects of immune defense and, as such, constitute potential targets for therapeutic intervention through rational drug design. Indeed, arrest of these signals...

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Detalles Bibliográficos
Autores principales: Wallach, David, Arumugam, Thangavelu U, Boldin, Mark P, Cantarella, Giuseppina, Ganesh, Koluman A, Goltsev, Yuri, Goncharov, Tanya M, Kovalenko, Andrew V, Rajput, Akhil, Varfolomeev, Eugene E, Zhang, Si Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3240160/
https://www.ncbi.nlm.nih.gov/pubmed/12110139
http://dx.doi.org/10.1186/ar585