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Synergistic Roles of Eukaryotic Translation Elongation Factors 1Bγ and 1A in Stimulation of Tombusvirus Minus-Strand Synthesis

Host factors are recruited into viral replicase complexes to aid replication of plus-strand RNA viruses. In this paper, we show that deletion of eukaryotic translation elongation factor 1Bgamma (eEF1Bγ) reduces Tomato bushy stunt virus (TBSV) replication in yeast host. Also, knock down of eEF1Bγ lev...

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Detalles Bibliográficos
Autores principales: Sasvari, Zsuzsanna, Izotova, Lara, Kinzy, Terri Goss, Nagy, Peter D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3240602/
https://www.ncbi.nlm.nih.gov/pubmed/22194687
http://dx.doi.org/10.1371/journal.ppat.1002438