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A Dominant Negative Zebrafish Ahr2 Partially Protects Developing Zebrafish from Dioxin Toxicity
The toxicity by 2,3,7,8 tetrachlorodibenzo-p-dioxin (TCDD) is thought to be caused by activation of the aryl hydrocarbon receptor (AHR). However, our understanding of how AHR activation by TCDD leads to toxic effects is poor. Ideally we would like to manipulate AHR activity in specific tissues and a...
Autores principales: | Lanham, Kevin A., Prasch, Amy L., Weina, Kasia M., Peterson, Richard E., Heideman, Warren |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3240621/ https://www.ncbi.nlm.nih.gov/pubmed/22194803 http://dx.doi.org/10.1371/journal.pone.0028020 |
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