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Single Cell Analysis Facilitates Staging of Blimp1-Dependent Primordial Germ Cells Derived from Mouse Embryonic Stem Cells

The cell intrinsic programming that regulates mammalian primordial germ cell (PGC) development in the pre-gonadal stage is challenging to investigate. To overcome this we created a transgene-free method for generating PGCs in vitro (iPGCs) from mouse embryonic stem cells (ESCs). Using labeling for S...

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Detalles Bibliográficos
Autores principales: Vincent, John J., Li, Ziwei, Lee, Serena A., Liu, Xian, Etter, Marisabel O., Diaz-Perez, Silvia V., Taylor, Sara K., Gkountela, Sofia, Lindgren, Anne G., Clark, Amander T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3240638/
https://www.ncbi.nlm.nih.gov/pubmed/22194959
http://dx.doi.org/10.1371/journal.pone.0028960