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Single Cell Analysis Facilitates Staging of Blimp1-Dependent Primordial Germ Cells Derived from Mouse Embryonic Stem Cells
The cell intrinsic programming that regulates mammalian primordial germ cell (PGC) development in the pre-gonadal stage is challenging to investigate. To overcome this we created a transgene-free method for generating PGCs in vitro (iPGCs) from mouse embryonic stem cells (ESCs). Using labeling for S...
Autores principales: | Vincent, John J., Li, Ziwei, Lee, Serena A., Liu, Xian, Etter, Marisabel O., Diaz-Perez, Silvia V., Taylor, Sara K., Gkountela, Sofia, Lindgren, Anne G., Clark, Amander T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3240638/ https://www.ncbi.nlm.nih.gov/pubmed/22194959 http://dx.doi.org/10.1371/journal.pone.0028960 |
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