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MicroRNA-449a Overexpression, Reduced NOTCH1 Signals and Scarce Goblet Cells Characterize the Small Intestine of Celiac Patients

MiRNAs play a relevant role in regulating gene expression in a variety of physiological and pathological conditions including autoimmune disorders. MiRNAs are also important in the differentiation and function of the mouse intestinal epithelium. Our study was aimed to look for miRNA-based modulation...

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Detalles Bibliográficos
Autores principales: Capuano, Marina, Iaffaldano, Laura, Tinto, Nadia, Montanaro, Donatella, Capobianco, Valentina, Izzo, Valentina, Tucci, Francesca, Troncone, Giancarlo, Greco, Luigi, Sacchetti, Lucia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3240641/
https://www.ncbi.nlm.nih.gov/pubmed/22194996
http://dx.doi.org/10.1371/journal.pone.0029094