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Murine and Human Myogenic Cells Identified by Elevated Aldehyde Dehydrogenase Activity: Implications for Muscle Regeneration and Repair

BACKGROUND: Despite the initial promise of myoblast transfer therapy to restore dystrophin in Duchenne muscular dystrophy patients, clinical efficacy has been limited, primarily by poor cell survival post-transplantation. Murine muscle derived stem cells (MDSCs) isolated from slowly adhering cells (...

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Detalles Bibliográficos
Autores principales: Vella, Joseph B., Thompson, Seth D., Bucsek, Mark J., Song, Minjung, Huard, Johnny
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3240661/
https://www.ncbi.nlm.nih.gov/pubmed/22195027
http://dx.doi.org/10.1371/journal.pone.0029226