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Protective Role of Toll-like Receptor 4 in Experimental Gonococcal Infection of Female Mice

Neisseria gonorrhoeae is a common bacterial sexually transmitted infection. Like all Gram-negative bacteria, the outer membrane of the gonococcus is rich in endotoxin, a known ligand for Toll-like receptor (TLR)-4. However, the role of endotoxin and its cognate receptor TLR4 in the mucosal response...

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Detalles Bibliográficos
Autores principales: Packiam, Mathanraj, Wu, Hong, Veit, Sandra J., Mavrogiorgos, Nikolaos, Jerse, Ann E., Ingalls, Robin R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3240729/
https://www.ncbi.nlm.nih.gov/pubmed/21937985
http://dx.doi.org/10.1038/mi.2011.38