In vitro and intrathecal siRNA mediated K(V)1.1 knock-down in primary sensory neurons

K(V)1.1 is a Shaker homologue K(+) channel that contributes to the juxta-paranodal membrane conductance in myelinated axons, and is blocked by fampridine (4-aminopyridine), used to treat the symptoms of multiple sclerosis. The present experiments investigate K(V)1.1 function in primary sensory neuro...

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Detalles Bibliográficos
Autores principales: Baker, Mark D., Chen, Ya-Chun, Shah, Syed U., Okuse, Kenji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3240745/
https://www.ncbi.nlm.nih.gov/pubmed/21903165
http://dx.doi.org/10.1016/j.mcn.2011.08.007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3240745/
https://www.ncbi.nlm.nih.gov/pubmed/21903165
http://dx.doi.org/10.1016/j.mcn.2011.08.007

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