Cargando…
In vitro and intrathecal siRNA mediated K(V)1.1 knock-down in primary sensory neurons
K(V)1.1 is a Shaker homologue K(+) channel that contributes to the juxta-paranodal membrane conductance in myelinated axons, and is blocked by fampridine (4-aminopyridine), used to treat the symptoms of multiple sclerosis. The present experiments investigate K(V)1.1 function in primary sensory neuro...
| Autores principales: | , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Academic Press
2011
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3240745/ https://www.ncbi.nlm.nih.gov/pubmed/21903165 http://dx.doi.org/10.1016/j.mcn.2011.08.007 |