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Role of blood cell-associated angiotensin II type 1 receptors in the cerebral microvascular response to ischemic stroke during angiotensin-induced hypertension

BACKGROUND: Angiotensin II type 1 receptor (AT1R) blockers lower the incidence of ischemic stroke in hypertensive patients and attenuate brain inflammation and injury in animal models. Although AT1R on both blood cells (BC) and vascular endothelial cells (EC) can be activated by angiotensin II (Ang...

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Detalles Bibliográficos
Autores principales: Nagai, Mutsumi, Terao, Satoshi, Vital, Shantel A, Rodrigues, Stephen F, Yilmaz, Gokhan, Granger, D Neil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3240825/
https://www.ncbi.nlm.nih.gov/pubmed/22087550
http://dx.doi.org/10.1186/2040-7378-3-15