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Role of blood cell-associated angiotensin II type 1 receptors in the cerebral microvascular response to ischemic stroke during angiotensin-induced hypertension
BACKGROUND: Angiotensin II type 1 receptor (AT1R) blockers lower the incidence of ischemic stroke in hypertensive patients and attenuate brain inflammation and injury in animal models. Although AT1R on both blood cells (BC) and vascular endothelial cells (EC) can be activated by angiotensin II (Ang...
Autores principales: | Nagai, Mutsumi, Terao, Satoshi, Vital, Shantel A, Rodrigues, Stephen F, Yilmaz, Gokhan, Granger, D Neil |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3240825/ https://www.ncbi.nlm.nih.gov/pubmed/22087550 http://dx.doi.org/10.1186/2040-7378-3-15 |
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