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Visualization of plasmid delivery to keratinocytes in mouse and human epidermis

The accessibility of skin makes it an ideal target organ for nucleic acid-based therapeutics; however, effective patient-friendly delivery remains a major obstacle to clinical utility. A variety of limited and inefficient methods of delivering nucleic acids to keratinocytes have been demonstrated; f...

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Detalles Bibliográficos
Autores principales: González-González, Emilio, Kim, Yeu-Chun, Speaker, Tycho J., Hickerson, Robyn P., Spitler, Ryan, Birchall, James C., Lara, Maria Fernanda, Hu, Rong-hua, Liang, Yanhua, Kirkiles-Smith, Nancy, Prausnitz, Mark R., Milstone, Leonard M., Contag, Christopher H., Kaspar, Roger L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3240989/
https://www.ncbi.nlm.nih.gov/pubmed/22355673
http://dx.doi.org/10.1038/srep00158