Structural insights into the molecular ruler mechanism of the endoplasmic reticulum aminopeptidase ERAP1

Endoplasmic reticulum aminopeptidase 1 (ERAP1) is an essential component of the immune system, because it trims peptide precursors and generates the N--restricted epitopes. To examine ERAP1's unique properties of length- and sequence-dependent processing of antigen precursors, we report a 2.3 Å...

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Detalles Bibliográficos
Autores principales: Gandhi, Amit, Lakshminarasimhan, Damodharan, Sun, Yixin, Guo, Hwai-Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3240994/
https://www.ncbi.nlm.nih.gov/pubmed/22355701
http://dx.doi.org/10.1038/srep00186

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3240994/
https://www.ncbi.nlm.nih.gov/pubmed/22355701
http://dx.doi.org/10.1038/srep00186

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