Cdc14b regulates mammalian RNA polymerase II and represses cell cycle transcription

Cdc14 is an essential phosphatase in yeast but its role in the mammalian cell cycle remains obscure. We report here that Cdc14b-knockout cells display unscheduled induction of multiple cell cycle regulators resulting in early entry into DNA replication and mitosis from quiescence. Cdc14b dephosphory...

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Detalles Bibliográficos
Autores principales: Guillamot, María, Manchado, Eusebio, Chiesa, Massimo, Gómez-López, Gonzalo, Pisano, David G., Sacristán, María P., Malumbres, Marcos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3240995/
https://www.ncbi.nlm.nih.gov/pubmed/22355704
http://dx.doi.org/10.1038/srep00189

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3240995/
https://www.ncbi.nlm.nih.gov/pubmed/22355704
http://dx.doi.org/10.1038/srep00189

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