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Toll-like receptor 3 upregulation by type I interferon in healthy and scleroderma dermal fibroblasts
INTRODUCTION: Increased levels of genes in the type I interferon (IFN) pathway have been observed in patients with systemic sclerosis (SSc), or scleroderma. How type I IFN regulates the dermal fibroblast and its participation in the development of dermal fibrosis is not known. We hypothesized that o...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3241348/ https://www.ncbi.nlm.nih.gov/pubmed/21223583 http://dx.doi.org/10.1186/ar3221 |