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Change in CD3 positive T-cell expression in psoriatic arthritis synovium correlates with change in DAS28 and magnetic resonance imaging synovitis scores following initiation of biologic therapy - a single centre, open-label study

INTRODUCTION: With the development of increasing numbers of potential therapeutic agents in inflammatory disease comes the need for effective biomarkers to help screen for drug efficacy and optimal dosing regimens early in the clinical trial process. This need has been recognized by the Outcome Meas...

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Detalles Bibliográficos
Autores principales: Pontifex, Eliza K, Gerlag, Danielle M, Gogarty, Martina, Vinkenoog, Marjolein, Gibbs, Adrian, Burgman, Ilse, Fearon, Ursula, Bresnihan, Barry, Tak, Paul Peter, Gibney, Robin G, Veale, Douglas J, FitzGerald, Oliver
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3241351/
https://www.ncbi.nlm.nih.gov/pubmed/21272347
http://dx.doi.org/10.1186/ar3228