The involvement of interleukin-1 and interleukin-4 in the response of human annulus fibrosus cells to cyclic tensile strain: an altered mechanotransduction pathway with degeneration

INTRODUCTION: Recent evidence suggests that intervertebral disc (IVD) cells derived from degenerative tissue are unable to respond to physiologically relevant mechanical stimuli in the 'normal' anabolic manner, but instead respond by increasing matrix catabolism. Understanding the nature o...

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Detalles Bibliográficos
Autores principales: Gilbert, Hamish TJ, Hoyland, Judith A, Freemont, Anthony J, Millward-Sadler, Sarah J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3241352/
https://www.ncbi.nlm.nih.gov/pubmed/21276216
http://dx.doi.org/10.1186/ar3229

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3241352/
https://www.ncbi.nlm.nih.gov/pubmed/21276216
http://dx.doi.org/10.1186/ar3229

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