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Expression of K(2P)5.1 potassium channels on CD4(+ )T lymphocytes correlates with disease activity in rheumatoid arthritis patients

INTRODUCTION: CD4(+ )T cells express K(2P)5.1 (TWIK-related acid-sensitive potassium channel 2 (TASK2); KCNK5), a member of the two-pore domain potassium channel family, which has been shown to influence T cell effector functions. Recently, it was shown that K(2P)5.1 is upregulated upon (autoimmune)...

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Detalles Bibliográficos
Autores principales: Bittner, Stefan, Bobak, Nicole, Feuchtenberger, Martin, Herrmann, Alexander M, Göbel, Kerstin, Kinne, Raimund W, Hansen, Anker J, Budde, Thomas, Kleinschnitz, Christoph, Frey, Oliver, Tony, Hans-Peter, Wiendl, Heinz, Meuth, Sven G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3241365/
https://www.ncbi.nlm.nih.gov/pubmed/21314928
http://dx.doi.org/10.1186/ar3245