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Modulation of transforming growth factor beta signalling pathway genes by transforming growth factor beta in human osteoarthritic chondrocytes: involvement of Sp1 in both early and late response cells to transforming growth factor beta

INTRODUCTION: Transforming growth factor beta (TGFβ) plays a central role in morphogenesis, growth, and cell differentiation. This cytokine is particularly important in cartilage where it regulates cell proliferation and extracellular matrix synthesis. While the action of TGFβ on chondrocyte metabol...

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Detalles Bibliográficos
Autores principales: Baugé, Catherine, Cauvard, Olivier, Leclercq, Sylvain, Galéra, Philippe, Boumédiene, Karim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3241367/
https://www.ncbi.nlm.nih.gov/pubmed/21324108
http://dx.doi.org/10.1186/ar3247