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Blockade of Toll-like receptor 2 prevents spontaneous cytokine release from rheumatoid arthritis ex vivo synovial explant cultures

INTRODUCTION: The aim of this study was to examine the effect of blocking Toll-like receptor 2 (TLR2) in rheumatoid arthritis (RA) synovial cells. METHODS: RA synovial tissue biopsies, obtained under direct visualization at arthroscopy, were established as synovial explant cultures ex vivo or snap f...

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Detalles Bibliográficos
Autores principales: Nic An Ultaigh, Sinéad, Saber, Tajvur P, McCormick, Jennifer, Connolly, Mary, Dellacasagrande, Jerome, Keogh, Brian, McCormack, William, Reilly, Mary, O'Neill, Luke A, McGuirk, Peter, Fearon, Ursula, Veale, Douglas J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3241377/
https://www.ncbi.nlm.nih.gov/pubmed/21345222
http://dx.doi.org/10.1186/ar3261