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PPM-1, a PP2Cα/β phosphatase, Regulates Axon Termination and Synapse Formation in Caenorhabditis elegans

The PHR (Pam/Highwire/RPM-1) proteins are evolutionarily conserved ubiquitin ligases that regulate axon guidance and synapse formation in Caenorhabditis elegans, Drosophila, zebrafish, and mice. In C. elegans, RPM-1 (Regulator of Presynaptic Morphology-1) functions in synapse formation, axon guidanc...

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Detalles Bibliográficos
Autores principales: Tulgren, Erik D., Baker, Scott T., Rapp, Laramie, Gurney, Allison M., Grill, Brock
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3241410/
https://www.ncbi.nlm.nih.gov/pubmed/21968191
http://dx.doi.org/10.1534/genetics.111.134791