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Environment-Sensitive Epigenetics and the Heritability of Complex Diseases
Genome-wide association studies have thus far failed to explain the observed heritability of complex human diseases. This is referred to as the “missing heritability” problem. However, these analyses have usually neglected to consider a role for epigenetic variation, which has been associated with m...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Genetics Society of America
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3241426/ https://www.ncbi.nlm.nih.gov/pubmed/21968193 http://dx.doi.org/10.1534/genetics.111.131912 |