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Environment-Sensitive Epigenetics and the Heritability of Complex Diseases

Genome-wide association studies have thus far failed to explain the observed heritability of complex human diseases. This is referred to as the “missing heritability” problem. However, these analyses have usually neglected to consider a role for epigenetic variation, which has been associated with m...

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Detalles Bibliográficos
Autores principales: Furrow, Robert E., Christiansen, Freddy B., Feldman, Marcus W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3241426/
https://www.ncbi.nlm.nih.gov/pubmed/21968193
http://dx.doi.org/10.1534/genetics.111.131912