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Organelle trafficking of chimeric ribozymes and genetic manipulation of mitochondria

With the expansion of the RNA world, antisense strategies have become widespread to manipulate nuclear gene expression but organelle genetic systems have remained aside. The present work opens the field to mitochondria. We demonstrate that customized RNAs expressed from a nuclear transgene and drive...

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Detalles Bibliográficos
Autores principales: Val, Romain, Wyszko, Eliza, Valentin, Clarisse, Szymanski, Maciej, Cosset, Anne, Alioua, Malek, Dreher, Theo W., Barciszewski, Jan, Dietrich, André
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3241634/
https://www.ncbi.nlm.nih.gov/pubmed/21768127
http://dx.doi.org/10.1093/nar/gkr580