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Organelle trafficking of chimeric ribozymes and genetic manipulation of mitochondria
With the expansion of the RNA world, antisense strategies have become widespread to manipulate nuclear gene expression but organelle genetic systems have remained aside. The present work opens the field to mitochondria. We demonstrate that customized RNAs expressed from a nuclear transgene and drive...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3241634/ https://www.ncbi.nlm.nih.gov/pubmed/21768127 http://dx.doi.org/10.1093/nar/gkr580 |