Reporter mRNAs cleaved by Rnt1p are exported and degraded in the cytoplasm

For most protein coding genes, termination of transcription by RNA polymerase II is preceded by an endonucleolytic cleavage of the nascent transcript. The 3′ product of this cleavage is rapidly degraded via the 5′ exoribonuclease Rat1p which is thought to destabilize the RNA polymerase II complex. I...

Descripción completa

Detalles Bibliográficos
Autores principales: Meaux, Stacie, Lavoie, Mathieu, Gagnon, Jules, Abou Elela, Sherif, van Hoof, Ambro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3241649/
https://www.ncbi.nlm.nih.gov/pubmed/21821655
http://dx.doi.org/10.1093/nar/gkr627

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3241649/
https://www.ncbi.nlm.nih.gov/pubmed/21821655
http://dx.doi.org/10.1093/nar/gkr627

Ejemplares similares