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The DEAH-box RNA helicase RHAU binds an intramolecular RNA G-quadruplex in TERC and associates with telomerase holoenzyme

Guanine-quadruplexes (G4) consist of non-canonical four-stranded helical arrangements of guanine-rich nucleic acid sequences. The bulky and thermodynamically stable features of G4 structures have been shown in many respects to affect normal nucleic acid metabolism. In vivo conversion of G4 structure...

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Detalles Bibliográficos
Autores principales: Lattmann, Simon, Stadler, Michael B., Vaughn, James P., Akman, Steven A., Nagamine, Yoshikuni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3241650/
https://www.ncbi.nlm.nih.gov/pubmed/21846770
http://dx.doi.org/10.1093/nar/gkr630