Synthesis, base pairing properties and trans-lesion synthesis by reverse transcriptases of oligoribonucleotides containing the oxidatively damaged base 5-hydroxycytidine

The synthesis of a caged RNA phosphoramidite building block containing the oxidatively damaged base 5-hydroxycytidine (5-HOrC) has been accomplished. To determine the effect of this highly mutagenic lesion on complementary base recognition and coding properties, this building block was incorporated...

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Detalles Bibliográficos
Autores principales: Küpfer, Pascal A., Leumann, Christian J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3241664/
https://www.ncbi.nlm.nih.gov/pubmed/21852326
http://dx.doi.org/10.1093/nar/gkr673

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3241664/
https://www.ncbi.nlm.nih.gov/pubmed/21852326
http://dx.doi.org/10.1093/nar/gkr673

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