Probing the Production of Amidated Peptides following Genetic and Dietary Copper Manipulations

Amidated neuropeptides play essential roles throughout the nervous and endocrine systems. Mice lacking peptidylglycine α-amidating monooxygenase (PAM), the only enzyme capable of producing amidated peptides, are not viable. In the amidation reaction, the reactant (glycine-extended peptide) is conver...

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Detalles Bibliográficos
Autores principales: Yin, Ping, Bousquet-Moore, Danielle, Annangudi, Suresh P., Southey, Bruce R., Mains, Richard E., Eipper, Betty A., Sweedler, Jonathan V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3241674/
https://www.ncbi.nlm.nih.gov/pubmed/22194882
http://dx.doi.org/10.1371/journal.pone.0028679

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3241674/
https://www.ncbi.nlm.nih.gov/pubmed/22194882
http://dx.doi.org/10.1371/journal.pone.0028679

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