Neutrophil Extracellular Trap Formation Is Associated with IL-1β and Autophagy-Related Signaling in Gout

BACKGROUND: Gout is a prevalent inflammatory arthritis affecting 1–2% of adults characterized by activation of innate immune cells by monosodium urate (MSU) crystals resulting in the secretion of interleukin-1β (IL-1β). Since neutrophils play a major role in gout we sought to determine whether their...

Descripción completa

Detalles Bibliográficos
Autores principales: Mitroulis, Ioannis, Kambas, Konstantinos, Chrysanthopoulou, Akrivi, Skendros, Panagiotis, Apostolidou, Eirini, Kourtzelis, Ioannis, Drosos, Georgios I., Boumpas, Dimitrios T., Ritis, Konstantinos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3241704/
https://www.ncbi.nlm.nih.gov/pubmed/22195044
http://dx.doi.org/10.1371/journal.pone.0029318

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3241704/
https://www.ncbi.nlm.nih.gov/pubmed/22195044
http://dx.doi.org/10.1371/journal.pone.0029318

Ejemplares similares