Distinct intracellular motifs of Delta mediate its ubiquitylation and activation by Mindbomb1 and Neuralized

DSL proteins are transmembrane ligands of the Notch receptor. They associate with a RING (really interesting new gene) family E3 ubiquitin ligase, either Neuralized (Neur) or Mindbomb 1 (Mib1), as a prerequisite to signaling. Although Neur and Mib1 stimulate internalization of DSL ligands, it is not...

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Detalles Bibliográficos
Autores principales: Daskalaki, Aikaterini, Shalaby, Nevine A., Kux, Kristina, Tsoumpekos, Giorgos, Tsibidis, George D., Muskavitch, Marc A.T., Delidakis, Christos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2011
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3241720/
https://www.ncbi.nlm.nih.gov/pubmed/22162135
http://dx.doi.org/10.1083/jcb.201105166

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3241720/
https://www.ncbi.nlm.nih.gov/pubmed/22162135
http://dx.doi.org/10.1083/jcb.201105166

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