Live imaging of apoptosis in a novel transgenic mouse highlights its role in neural tube closure

Many cells die during development, tissue homeostasis, and disease. Dysregulation of apoptosis leads to cranial neural tube closure (NTC) defects like exencephaly, although the mechanism is unclear. Observing cells undergoing apoptosis in a living context could help elucidate their origin, behavior,...

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Detalles Bibliográficos
Autores principales: Yamaguchi, Yoshifumi, Shinotsuka, Naomi, Nonomura, Keiko, Takemoto, Kiwamu, Kuida, Keisuke, Yosida, Hiroki, Miura, Masayuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2011
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3241723/
https://www.ncbi.nlm.nih.gov/pubmed/22162136
http://dx.doi.org/10.1083/jcb.201104057

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3241723/
https://www.ncbi.nlm.nih.gov/pubmed/22162136
http://dx.doi.org/10.1083/jcb.201104057

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