Triterpenoid modulation of IL-17 and Nrf-2 expression ameliorates neuroinflammation and promotes remyelination in autoimmune encephalomyelitis

Inflammatory cytokines and endogenous anti-oxidants are variables affecting disease progression in multiple sclerosis (MS). Here we demonstrate the dual capacity of triterpenoids to simultaneously repress production of IL-17 and other pro-inflammatory mediators while exerting neuroprotective effects...

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Detalles Bibliográficos
Autores principales: Pareek, Tej K., Belkadi, Abdelmadjid, Kesavapany, Sashi, Zaremba, Anita, Loh, Sook L., Bai, Lianhua, Cohen, Mark L., Meyer, Colin, Liby, Karen T., Miller, Robert H., Sporn, Michael B., Letterio, John J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3242013/
https://www.ncbi.nlm.nih.gov/pubmed/22355716
http://dx.doi.org/10.1038/srep00201

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3242013/
https://www.ncbi.nlm.nih.gov/pubmed/22355716
http://dx.doi.org/10.1038/srep00201

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