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Apo and InsP(3)-bound crystal structures of the ligand-binding domain of an InsP(3) receptor
We report the crystal structures of the ligand-binding domain (LBD) of a rat inositol 1,4,5-trisphosphate (InsP(3)) receptor (InsP(3)R) in its apo and InsP(3)-bound conformations. Comparison of these two conformations reveals that LBD's first β-trefoil fold (β-TF1) and armadillo repeat fold (AR...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3242432/ https://www.ncbi.nlm.nih.gov/pubmed/21892169 http://dx.doi.org/10.1038/nsmb.2112 |