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Apo and InsP(3)-bound crystal structures of the ligand-binding domain of an InsP(3) receptor

We report the crystal structures of the ligand-binding domain (LBD) of a rat inositol 1,4,5-trisphosphate (InsP(3)) receptor (InsP(3)R) in its apo and InsP(3)-bound conformations. Comparison of these two conformations reveals that LBD's first β-trefoil fold (β-TF1) and armadillo repeat fold (AR...

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Detalles Bibliográficos
Autores principales:	Lin, Chun-Chi, Baek, Kyuwon, Lu, Zhe
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2011
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3242432/ https://www.ncbi.nlm.nih.gov/pubmed/21892169 http://dx.doi.org/10.1038/nsmb.2112

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