Negative Correlation between Expression Level and Evolutionary Rate of Long Intergenic Noncoding RNAs

Mammalian genomes contain numerous genes for long noncoding RNAs (lncRNAs). The functions of the lncRNAs remain largely unknown but their evolution appears to be constrained by purifying selection, albeit relatively weakly. To gain insights into the mode of evolution and the functional range of the...

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Detalles Bibliográficos
Autores principales: Managadze, David, Rogozin, Igor B., Chernikova, Diana, Shabalina, Svetlana A., Koonin, Eugene V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3242500/
https://www.ncbi.nlm.nih.gov/pubmed/22071789
http://dx.doi.org/10.1093/gbe/evr116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3242500/
https://www.ncbi.nlm.nih.gov/pubmed/22071789
http://dx.doi.org/10.1093/gbe/evr116

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