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Negative Correlation between Expression Level and Evolutionary Rate of Long Intergenic Noncoding RNAs
Mammalian genomes contain numerous genes for long noncoding RNAs (lncRNAs). The functions of the lncRNAs remain largely unknown but their evolution appears to be constrained by purifying selection, albeit relatively weakly. To gain insights into the mode of evolution and the functional range of the...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3242500/ https://www.ncbi.nlm.nih.gov/pubmed/22071789 http://dx.doi.org/10.1093/gbe/evr116 |