Nedd4-dependent lysine-11-linked polyubiquitination of the tumour suppressor Beclin 1

Beclin 1, a subunit of the class III phosphatidylinositol 3-kinase complex, is a tumour suppressor with a central role in endocytic trafficking, cytokinesis and the cross-regulation between autophagy and apoptosis. Interestingly, not only reduced expression but also overexpression of Beclin 1 is cor...

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Detalles Bibliográficos
Autores principales: Platta, Harald W., Abrahamsen, Hilde, Thoresen, Sigrid B., Stenmark, Harald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3242507/
https://www.ncbi.nlm.nih.gov/pubmed/21936852
http://dx.doi.org/10.1042/BJ20111424

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3242507/
https://www.ncbi.nlm.nih.gov/pubmed/21936852
http://dx.doi.org/10.1042/BJ20111424

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