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Relaxin-like factor (RLF)/insulin-like peptide 3 (INSL3) is secreted from testicular Leydig cells as a monomeric protein comprising three domains B–C–A with full biological activity in boars

RLF (relaxin-like factor), also known as INSL3 (insulin-like peptide 3), is a novel member of the relaxin/insulin gene family that is expressed in testicular Leydig cells. Despite the implicated role of RLF/INSL3 in testis development, its native conformation remains unknown. In the present paper we...

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Detalles Bibliográficos
Autores principales: Minagawa, Itaru, Fukuda, Masafumi, Ishige, Hisako, Kohriki, Hiroshi, Shibata, Masatoshi, Park, Enoch Y., Kawarasaki, Tatsuo, Kohsaka, Tetsuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3242508/
https://www.ncbi.nlm.nih.gov/pubmed/21899516
http://dx.doi.org/10.1042/BJ20111107