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Systemically administered PEDF against primary and secondary tumours in a clinically relevant osteosarcoma model

BACKGROUND: Pigment epithelium-derived factor (PEDF) is an endogenous glycoprotein with a potential role as a therapeutic for osteosarcoma. Animal studies have demonstrated the biological effects of PEDF on osteosarcoma; however, these results are difficult to extrapolate for human use due to the ch...

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Detalles Bibliográficos
Autores principales: Broadhead, M L, Dass, C R, Choong, P F M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3242526/
https://www.ncbi.nlm.nih.gov/pubmed/21979423
http://dx.doi.org/10.1038/bjc.2011.410