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Systemically administered PEDF against primary and secondary tumours in a clinically relevant osteosarcoma model
BACKGROUND: Pigment epithelium-derived factor (PEDF) is an endogenous glycoprotein with a potential role as a therapeutic for osteosarcoma. Animal studies have demonstrated the biological effects of PEDF on osteosarcoma; however, these results are difficult to extrapolate for human use due to the ch...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3242526/ https://www.ncbi.nlm.nih.gov/pubmed/21979423 http://dx.doi.org/10.1038/bjc.2011.410 |