Immunotherapy augments the effect of 5-azacytidine on HPV16-associated tumours with different MHC class I-expression status

BACKGROUND: Epigenetic mechanisms have important roles in the tumour escape from immune responses, such as in MHC class I downregulation or altered expression of other components involved in antigen presentation. Chemotherapy with DNA methyltransferase inhibitors (DNMTi) can thus influence the tumou...

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Detalles Bibliográficos
Autores principales: Šímová, J, Polláková, V, Indrová, M, Mikyšková, R, Bieblová, J, Štěpánek, I, Bubeník, J, Reiniš, M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Translational Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3242529/
https://www.ncbi.nlm.nih.gov/pubmed/22015556
http://dx.doi.org/10.1038/bjc.2011.428

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3242529/
https://www.ncbi.nlm.nih.gov/pubmed/22015556
http://dx.doi.org/10.1038/bjc.2011.428

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