Influence of glioma tumour microenvironment on the transport of ANG1005 via low-density lipoprotein receptor-related protein 1

BACKGROUND: ANG1005 consists of three molecules of paclitaxel conjugated via ester bonds to the 19-amino-acid peptide Angiopep-2. The new chemical agent has been shown to cross the blood–brain barrier (BBB) by receptor-mediated transcytosis via low-density lipoprotein receptor-related protein 1 (LRP...

Descripción completa

Detalles Bibliográficos
Autores principales: Bertrand, Y, Currie, J-C, Poirier, J, Demeule, M, Abulrob, A, Fatehi, D, Stanimirovic, D, Sartelet, H, Castaigne, J-P, Béliveau, R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Translational Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3242593/
https://www.ncbi.nlm.nih.gov/pubmed/22027709
http://dx.doi.org/10.1038/bjc.2011.427

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3242593/
https://www.ncbi.nlm.nih.gov/pubmed/22027709
http://dx.doi.org/10.1038/bjc.2011.427

Ejemplares similares