Idebenone and Resveratrol Extend Lifespan and Improve Motor Function of HtrA2 Knockout Mice

Heterozygous loss-of-function mutation of the human gene for the mitochondrial protease HtrA2 has been associated with increased risk to develop mitochondrial dysfunction, a process known to contribute to neurodegenerative disorders such as Huntington's disease (HD) and Parkinson's disease...

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Detalles Bibliográficos
Autores principales: Gerhardt, Ellen, Gräber, Simone, Szegő, Éva M., Moisoi, Nicoleta, Martins, L. Miguel, Outeiro, Tiago F., Kermer, Pawel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3242749/
https://www.ncbi.nlm.nih.gov/pubmed/22205977
http://dx.doi.org/10.1371/journal.pone.0028855

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3242749/
https://www.ncbi.nlm.nih.gov/pubmed/22205977
http://dx.doi.org/10.1371/journal.pone.0028855

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