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Idebenone and Resveratrol Extend Lifespan and Improve Motor Function of HtrA2 Knockout Mice

Heterozygous loss-of-function mutation of the human gene for the mitochondrial protease HtrA2 has been associated with increased risk to develop mitochondrial dysfunction, a process known to contribute to neurodegenerative disorders such as Huntington's disease (HD) and Parkinson's disease...

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Detalles Bibliográficos
Autores principales:	Gerhardt, Ellen, Gräber, Simone, Szegő, Éva M., Moisoi, Nicoleta, Martins, L. Miguel, Outeiro, Tiago F., Kermer, Pawel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3242749/ https://www.ncbi.nlm.nih.gov/pubmed/22205977 http://dx.doi.org/10.1371/journal.pone.0028855

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