Farnesol-Induced Apoptosis in Candida albicans Is Mediated by Cdr1-p Extrusion and Depletion of Intracellular Glutathione

Farnesol is a key derivative in the sterol biosynthesis pathway in eukaryotic cells previously identified as a quorum sensing molecule in the human fungal pathogen Candida albicans. Recently, we demonstrated that above threshold concentrations, farnesol is capable of triggering apoptosis in C. albic...

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Detalles Bibliográficos
Autores principales: Zhu, Jingsong, Krom, Bastiaan P., Sanglard, Dominique, Intapa, Chaidan, Dawson, Clinton C., Peters, Brian M., Shirtliff, Mark E., Jabra-Rizk, Mary Ann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3242750/
https://www.ncbi.nlm.nih.gov/pubmed/22205973
http://dx.doi.org/10.1371/journal.pone.0028830

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3242750/
https://www.ncbi.nlm.nih.gov/pubmed/22205973
http://dx.doi.org/10.1371/journal.pone.0028830

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