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Binding of Tetracycline and Chlortetracycline to the Enzyme Trypsin: Spectroscopic and Molecular Modeling Investigations

Tetracycline (TC) and chlortetracycline (CTC) are common members of the widely used veterinary drug tetracyclines, the residue of which in the environment can enter human body, being potentially harmful. In this study, we establish a new strategy to probe the binding modes of TC and CTC with trypsin...

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Detalles Bibliográficos
Autores principales: Chi, Zhenxing, Liu, Rutao, Yang, Hongxu, Shen, Hengmei, Wang, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3242759/
https://www.ncbi.nlm.nih.gov/pubmed/22205948
http://dx.doi.org/10.1371/journal.pone.0028361