The Dynamin Chemical Inhibitor Dynasore Impairs Cholesterol Trafficking and Sterol-Sensitive Genes Transcription in Human HeLa Cells and Macrophages

Intracellular transport of cholesterol contributes to the regulation of cellular cholesterol homeostasis by mechanisms that are yet poorly defined. In this study, we characterized the impact of dynasore, a recently described drug that specifically inhibits the enzymatic activity of dynamin, a GTPase...

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Detalles Bibliográficos
Autores principales: Girard, Emmanuelle, Paul, Jean Louis, Fournier, Natalie, Beaune, Philippe, Johannes, Ludger, Lamaze, Christophe, Védie, Benoît
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3242776/
https://www.ncbi.nlm.nih.gov/pubmed/22205993
http://dx.doi.org/10.1371/journal.pone.0029042

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3242776/
https://www.ncbi.nlm.nih.gov/pubmed/22205993
http://dx.doi.org/10.1371/journal.pone.0029042

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