Cargando…
The Dynamin Chemical Inhibitor Dynasore Impairs Cholesterol Trafficking and Sterol-Sensitive Genes Transcription in Human HeLa Cells and Macrophages
Intracellular transport of cholesterol contributes to the regulation of cellular cholesterol homeostasis by mechanisms that are yet poorly defined. In this study, we characterized the impact of dynasore, a recently described drug that specifically inhibits the enzymatic activity of dynamin, a GTPase...
Autores principales: | Girard, Emmanuelle, Paul, Jean Louis, Fournier, Natalie, Beaune, Philippe, Johannes, Ludger, Lamaze, Christophe, Védie, Benoît |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3242776/ https://www.ncbi.nlm.nih.gov/pubmed/22205993 http://dx.doi.org/10.1371/journal.pone.0029042 |
Ejemplares similares
-
Dynasore - not just a dynamin inhibitor
por: Preta, Giulio, et al.
Publicado: (2015) -
Protective role of the dynamin inhibitor Dynasore against the cholesterol-dependent cytolysin of Trueperella pyogenes
por: Preta, Giulio, et al.
Publicado: (2015) -
Impact of Dynasore an Inhibitor of Dynamin II on Shigella flexneri Infection
por: Lum, Mabel, et al.
Publicado: (2013) -
Dynasore, a Dynamin Inhibitor, Inhibits Trypanosoma cruzi Entry into Peritoneal Macrophages
por: Barrias, Emile S., et al.
Publicado: (2010) -
Building a Better Dynasore: The Dyngo Compounds Potently Inhibit Dynamin and Endocytosis
por: McCluskey, Adam, et al.
Publicado: (2013)