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Divergent expression patterns of IL-4 and IL-13 define unique functions in allergic immunity

Interleukin 4 (IL-4) and IL-13 are critical for responses against parasitic helminthes. Here we used genetically engineered reporter mice to assess the temporal and spatial production of these cytokine in vivo. In lymph nodes, IL-4 was confined to T follicular helper (T(FH)) cells, however these cel...

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Detalles Bibliográficos
Autores principales: Liang, Hong-Erh, Reinhardt, R. Lee, Bando, Jennifer K., Sullivan, Brandon M., Ho, I-Cheng, Locksley, Richard M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3242938/
https://www.ncbi.nlm.nih.gov/pubmed/22138715
http://dx.doi.org/10.1038/ni.2182